Stars at the 75th Golden Globes wore black and made powerful speeches tackling sexual harassment and gender inequality.

The Time's Up campaign took the awards by storm, where a powerful speech from Oprah Winfrey stole the show and host Seth Meyer's jokes set the tone.

Actress and TV presenter Winfrey was awarded with the Cecil B DeMille lifetime achievement award and said she was "humbled" by it, and took the opportunity to "elevate what is happening" in Hollywood "instead of continually victimise ourselves".

"When something as big as what started to happen in October with Harvey Weinstein started to unfold I thought whoa whoa whoa whoa whoa," she said.

"So I think that wearing black in solidarity is one step. I think that what Time's Up is doing with a legal defence fund is a major step.

:: As It Happened: 75th Golden Globes

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"It was very important to all of us involved with Time's Up that it not just be about the women of Hollywood because we're already a privileged group but to extend to the women of the world because as I said tonight there isn't a culture, a race, a religion, a politic, a workplace that hasn't been affected by it."

But Winfrey wasn't the only one to tackle the elephant in the room, with most of the stars wearing black and making reference to the string of sexual harassment and assault accusations Hollywood witnessed this year.

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Actress Natalie Portman came on stage to announce the award for best director, and took the opportunity to remind everyone that only men had been nominated for the category.

"Here are all the male nominees," she said, while the men in question looked surprised.

Host Seth Meyers was also one of the evening's highlights, opening the ceremony with a monologue tackling all main political issues.

"Good evening ladies and gentlemen," he started by saying.

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"There's a new era under way. I can tell because it's been long since a white man has been nervous in Hollywood.

"For the men in the room, this will be the first time in three months where it won't be terrifying to hear your name read out loud."

But while serious issues stole some of the night's glamour, it was still a ceremony celebrating film.

The main winners of the night included Martin McDonagh's Three Billboards Outside Ebbing, Missouri which took home best drama, best screenplay and best actress in a drama for Frances McDormand.

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Her male counterpart was Gary Oldman, who picked up best actor in a drama for his portrayal of Winston Churchill in The Darkest Hour.

On the comedy or musical category, Saoirse Ronan's Lady Bird won best film and best actress.

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On the TV side it was all about Big Little Lies, with Sky Atlantic's short-form television series winning its category.

Other winners included The Marvelous Mrs Maisel for best TV comedy and The Handmaid's Tale for best TV drama.

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