Tributes have been paid to Republican senator John McCain after he died at the age of 81 following a battle with brain cancer.

Below are some of the reactions to death of the veteran politician who stood against Barack Obama in 2008.

:: Donald Trump

"My deepest sympathies and respect go out to the family of Senator John McCain," he said. "Our hearts and prayers are with you!"

:: James Mattis

The secretary of defence said the US had "lost a man who steadfastly represented the best ideals of our country".

:: Barack Obama

The former president said: "John McCain and I were members of different generations, came from completely different backgrounds, and competed at the highest level of politics.

"But we shared, for all our differences, a fidelity to something higher – the ideals for which generations of Americans and immigrants alike have fought, marched, and sacrificed. We saw our political battles, even, as a privilege, something noble, an opportunity to serve as stewards of those high ideals at home, and to advance them around the world.

"We saw this country as a place where anything is possible – and citizenship as our patriotic obligation to ensure it forever remains that way."

:: Joe Biden

"John McCain's life is proof that some truths are timeless. Character. Courage. Integrity. Honour. A life lived embodying those truths casts a long, long shadow," the former vice president said. "John McCain will cast a long shadow. His impact on America hasn't ended. Not even close. It will go on for many years to come."

He added: "America will miss John McCain. The world will miss John McCain. And I will miss him dearly."

:: George W Bush

The former president said: "Some lives are so vivid, it is difficult to imagine them ended. Some voices aer so vibrant, it is hard to think of them stilled. John McCain was a man of deep conviction and a patriot of the highest order. He was a piblic servant in the finest traditions of our country. And to me, he was a friend whom I'll deeply miss. Laura and I send our heartfelt sympathies to Cindy and the entire McCain family, and our thanks to God for the life of John McCain."

:: Sarah Palin

Mr McCain's 2008 running mate said: "Today we lost an American original. Sen. John McCain was a maverick and a fighter, never afraid to stand for his beliefs. John never took the easy path in life – and through sacrifice and suffering he inspired others to serve something greater than self.

"John McCain was my friend. I will remember the good times. My family and I send prayers for Cindy and the McCain family."

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